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Rosiglitazone Improves Insulin Sensitivity and Baroreflex Gain in Rats with Diet-Induced Obesity

Obesity decreases baroreflex gain (BRG); however, the mechanisms are unknown. We tested the hypothesis that impaired BRG is related to the concurrent insulin resistance, and, therefore, BRG would be improved after treatment with the insulin-sensitizing drug rosiglitazone. Male rats fed a high-fat di...

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Detalhes bibliográficos
Main Authors: Zhao, Ding, McCully, Belinda H., Brooks, Virginia L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464031/
https://ncbi.nlm.nih.gov/pubmed/22815534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.194738
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