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Sibutramine reduces feeding, body fat and improves insulin resistance in dietary-obese male Wistar rats independently of hypothalamic neuropeptide Y
1. We studied the effects of the novel noradrenaline and serotonin (5-HT) reuptake inhibitor sibutramine on feeding and body weight in a rat model of dietary obesity, and whether it interacts with hypothalamic neuropeptide Y (NPY) neurones. 2. Chow-fed and dietary-obese (DIO) male Wistar rats were g...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572745/ https://ncbi.nlm.nih.gov/pubmed/11309262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704030 |
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