The dual PPARα/γ agonist, ragaglitazar, improves insulin sensitivity and metabolic profile equally with pioglitazone in diabetic and dietary obese ZDF rats

1. In 6- and 10-week-old obesity-prone (fa/fa) Zucker diabetic fatty (ZDF) rats, effects of prevention and intervention therapies, respectively, were compared between PPARα/γ agonist, ragaglitazar (RAGA) and separate PPARγ and α agonists, pioglitazone (PIO) and bezafibrate (BF). 2. In a separate stu...

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Detalhes bibliográficos
Main Authors: Pickavance, Lucy C, Brand, Christian L, Wassermann, Karsten, Wilding, John P H
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576007/
https://ncbi.nlm.nih.gov/pubmed/15655531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706041
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