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Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression
The microtubule-associated protein tau (MAPT) is a pathological component of several neurodegenerative diseases and clinical dementias. Here, we have investigated the effects of a series of commercially available FDA-approved compounds and natural products on total tau protein levels using a cell-ba...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1570347/ https://ncbi.nlm.nih.gov/pubmed/16930453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-1-6 |
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