L-687,414, a low efficacy NMDA receptor glycine site partial agonist in vitro, does not prevent hippocampal LTP in vivo at plasma levels known to be neuroprotective

Ítems similars

• The anticonvulsant and behavioural profile of L-687,414, a partial agonist acting at the glycine modulatory site on the N-methyl-D-aspartate (NMDA) receptor complex.
  per: Tricklebank, M D, et al.
  Publicat: (1994)
• Lack of effect of L-687,414 ((+)-cis-4-methyl-HA-966), an NMDA receptor antagonist acting at the glycine site, on cerebral glucose metabolism and cortical neuronal morphology.
  per: Hargreaves, R. J., et al.
  Publicat: (1993)
• Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels
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  per: Tang, Tina Tze-Tsang, et al.
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• The glycine transport inhibitor sarcosine is an NMDA receptor co-agonist that differs from glycine
  per: Zhang, Hai Xia, et al.
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