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Dysbindin regulates hippocampal LTP by controlling NMDA receptor surface expression

Abnormalities in NMDA receptor (NMDAR) function have been implicated in schizophrenia. Here, we show that dysbindin, a schizophrenia-susceptibility gene widely expressed in the forebrain, controls the surface expression of NMDARs in a subunit-specific manner. Imaging analyses revealed a marked incre...

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Detalhes bibliográficos
Main Authors: Tang, Tina Tze-Tsang, Yang, Feng, Chen, Bo-Shiun, Lu, Yuan, Ji, Yuanyuan, Roche, Katherine W., Lu, Bai
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795512/
https://ncbi.nlm.nih.gov/pubmed/19955431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910499106
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