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Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in hippocampal neurons
Extracellular factors may act on cells in two distinct modes: an acute increase in concentration due to regulated secretion, or a gradual increase in concentration when secreted constitutively or from a distant source. We show that cellular responses to BDNF differ dramatically depending on how BDNF...
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| Publicado no: | Nat Neurosci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4780419/ https://ncbi.nlm.nih.gov/pubmed/20173744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2505 |
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