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The effect of glibenclamide on the production of interstitial adenosine by inhibiting ecto-5′-nucleotidase in rat hearts

1. Adenosine exerts cardioprotective effects on the ischaemic myocardium. The production of adenosine in the ischaemic myocardium is attributed primarily to the enzymatic dephosphorylation of adenosine 5′-monophosphate (AMP) by 5′-nucleotidase. We determined the activity of 5′-nucleotidase in rat he...

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Bibliografiske detaljer
Main Authors: Sato, Toshiaki, Obata, Toshio, Yamanaka, Yasumitsu, Arita, Makoto
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564982/
https://ncbi.nlm.nih.gov/pubmed/9375955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701424
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