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The effect of glibenclamide on the production of interstitial adenosine by inhibiting ecto-5′-nucleotidase in rat hearts

1. Adenosine exerts cardioprotective effects on the ischaemic myocardium. The production of adenosine in the ischaemic myocardium is attributed primarily to the enzymatic dephosphorylation of adenosine 5′-monophosphate (AMP) by 5′-nucleotidase. We determined the activity of 5′-nucleotidase in rat he...

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Bibliografski detalji
Glavni autori: Sato, Toshiaki, Obata, Toshio, Yamanaka, Yasumitsu, Arita, Makoto
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564982/
https://ncbi.nlm.nih.gov/pubmed/9375955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701424
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