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The effect of glibenclamide on the production of interstitial adenosine by inhibiting ecto-5′-nucleotidase in rat hearts

1. Adenosine exerts cardioprotective effects on the ischaemic myocardium. The production of adenosine in the ischaemic myocardium is attributed primarily to the enzymatic dephosphorylation of adenosine 5′-monophosphate (AMP) by 5′-nucleotidase. We determined the activity of 5′-nucleotidase in rat he...

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Detalhes bibliográficos
Main Authors: Sato, Toshiaki, Obata, Toshio, Yamanaka, Yasumitsu, Arita, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564982/
https://ncbi.nlm.nih.gov/pubmed/9375955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701424
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