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Inhibition by ATP of Hippocampal Synaptic Transmission Requires Localized Extracellular Catabolism by Ecto-Nucleotidases into Adenosine and Channeling to Adenosine A(1) Receptors

ATP analogs substituted in the γ-phosphorus (ATPγS, β,γ-imido-ATP, and β,γ-methylene-ATP) were used to probe the involvement of P(2) receptors in the modulation of synaptic transmission in the hippocampus, because their extracellular catabolism was virtually not detected in CA1 slices. ATP and γ-sub...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Cunha, Rodrigo A., Sebastião, Ana M., Ribeiro, J. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792930/
https://ncbi.nlm.nih.gov/pubmed/9482785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-06-01987.1998
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