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Inhibition by ATP of Hippocampal Synaptic Transmission Requires Localized Extracellular Catabolism by Ecto-Nucleotidases into Adenosine and Channeling to Adenosine A(1) Receptors

ATP analogs substituted in the γ-phosphorus (ATPγS, β,γ-imido-ATP, and β,γ-methylene-ATP) were used to probe the involvement of P(2) receptors in the modulation of synaptic transmission in the hippocampus, because their extracellular catabolism was virtually not detected in CA1 slices. ATP and γ-sub...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Cunha, Rodrigo A., Sebastião, Ana M., Ribeiro, J. A.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792930/
https://ncbi.nlm.nih.gov/pubmed/9482785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-06-01987.1998
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