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Pharmacological characterization of the sulphonylurea receptor in rat isolated aorta

1. The binding of the sulphonylurea [(3)H]-glibenclamide, a blocker of adenosine 5′-triphosphate (ATP)-sensitive K(+) channels (K(ATP) channels), was studied in endothelium-denuded rings from rat aorta. 2. [(3)H]-glibenclamide labelled two classes of binding sites with K(D) values of 20±5 nM and 32±...

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Bibliografiska uppgifter
Huvudupphovsmän: Löffler, Cornelia, Quast, Ulrich
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1997
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564480/
https://ncbi.nlm.nih.gov/pubmed/9031752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700919
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