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Lipids modulate ligand binding to sulphonylurea receptors

1. ATP-sensitive K(+) channels (K(ATP) channels) are complexes of inwardly rectifying K(+) channels (Kir6.x) and sulphonylurea receptors (SURs). Kir6.2-containing channels are closed by ATP binding to Kir6.2, and opened by MgADP binding to SUR. Channel activity is modulated by synthetic compounds su...

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Detalhes bibliográficos
Main Authors: Klein, Alexander, Lichtenberg, Jochen, Stephan, Damian, Quast, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576209/
https://ncbi.nlm.nih.gov/pubmed/15895108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706252
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