Structural Stability and Dynamics of an Amyloid-Forming Peptide GNNQQNY from the Yeast Prion Sup-35

A seven amino acid yeast prion sup-35 fragment (GNNQQNY) forms amyloid fibrils. The availability of its detailed atomic oligomeric structure makes it a good model for studying the early stage of aggregation. Here we perform long all-atom explicit solvent molecular simulations of various sizes and ar...

Full description

Saved in:
Bibliographic Details
Main Authors: Zheng, Jie, Ma, Buyong, Tsai, Chung-Jung, Nussinov, Ruth
Format: Artigo
Language:Inglês
Published: Biophysical Society 2006
Subjects:
Biophysical Theory and Modeling
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563778/
https://ncbi.nlm.nih.gov/pubmed/16679374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.083246
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items