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Structural Stability and Dynamics of an Amyloid-Forming Peptide GNNQQNY from the Yeast Prion Sup-35

A seven amino acid yeast prion sup-35 fragment (GNNQQNY) forms amyloid fibrils. The availability of its detailed atomic oligomeric structure makes it a good model for studying the early stage of aggregation. Here we perform long all-atom explicit solvent molecular simulations of various sizes and ar...

詳細記述

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書誌詳細
主要な著者: Zheng, Jie, Ma, Buyong, Tsai, Chung-Jung, Nussinov, Ruth
フォーマット: Artigo
言語:Inglês
出版事項: Biophysical Society 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563778/
https://ncbi.nlm.nih.gov/pubmed/16679374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.083246
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