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A Variational Model for Oligomer-Formation Process of GNNQQNY Peptide from Yeast Prion Protein Sup35

Many human neurodegenerative diseases are associated with the aggregation of insoluble amyloid-like fibrous proteins. However, the processes by which the randomly diffused monomer peptides aggregate into the highly regulated amyloid fibril structures are largely unknown. We proposed a residue-level...

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Bibliographische Detailangaben
Hauptverfasser: Qi, Xianghong, Hong, Liu, Zhang, Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274832/
https://ncbi.nlm.nih.gov/pubmed/22325283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.12.036
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