Characterizing the Assembly of the Sup35 Yeast Prion Fragment, GNNQQNY: Structural Changes Accompany a Fiber-to-Crystal Switch

Amyloid-like fibrils can be formed by many different proteins and peptides. The structural characteristics of these fibers are very similar to those of amyloid fibrils that are deposited in a number of protein misfolding diseases, including Alzheimer's disease and the transmissible spongiform e...

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Autores principales: Marshall, Karen E., Hicks, Matthew R., Williams, Thomas L., Hoffmann, Søren Vrønning, Rodger, Alison, Dafforn, Timothy R., Serpell, Louise C.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2010
Materias:
Protein
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808478/
https://ncbi.nlm.nih.gov/pubmed/20338855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.10.020
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