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Replication of Hepatitis C Virus (HCV) RNA in Mouse Embryonic Fibroblasts: Protein Kinase R (PKR)-Dependent and PKR-Independent Mechanisms for Controlling HCV RNA Replication and Mediating Interferon Activities

Hepatitis C virus (HCV) infection causes chronic hepatitis and is currently treated with alpha interferon (IFN-α)-based therapies. The underlying mechanisms of chronic HCV infection and IFN-based therapies, however, have not been defined. Protein kinase R (PKR) was implicated in the control of HCV r...

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Những tác giả chính:	Chang, Kyung-Soo, Cai, Zhaohui, Zhang, Chen, Sen, Ganes C., Williams, Bryan R. G., Luo, Guangxiang
Định dạng:	Artigo
Ngôn ngữ:	Inglês
Được phát hành:	American Society for Microbiology 2006
Những chủ đề:	Pathogenesis and Immunity
Truy cập trực tuyến:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1563689/ https://ncbi.nlm.nih.gov/pubmed/16840317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00586-06
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Replication of Hepatitis C Virus (HCV) RNA in Mouse Embryonic Fibroblasts: Protein Kinase R (PKR)-Dependent and PKR-Independent Mechanisms for Controlling HCV RNA Replication and Mediating Interferon Activities

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