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Replication of Hepatitis C Virus (HCV) RNA in Mouse Embryonic Fibroblasts: Protein Kinase R (PKR)-Dependent and PKR-Independent Mechanisms for Controlling HCV RNA Replication and Mediating Interferon Activities

Hepatitis C virus (HCV) infection causes chronic hepatitis and is currently treated with alpha interferon (IFN-α)-based therapies. The underlying mechanisms of chronic HCV infection and IFN-based therapies, however, have not been defined. Protein kinase R (PKR) was implicated in the control of HCV r...

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Detalhes bibliográficos
Main Authors: Chang, Kyung-Soo, Cai, Zhaohui, Zhang, Chen, Sen, Ganes C., Williams, Bryan R. G., Luo, Guangxiang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563689/
https://ncbi.nlm.nih.gov/pubmed/16840317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00586-06
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