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Activation of PKR by Bunyamwera Virus Is Independent of the Viral Interferon Antagonist NSs
Double-stranded RNA (dsRNA) is a by-product of viral RNA polymerase activity, and its recognition is one mechanism by which the innate immune system is activated. Cellular responses to dsRNA include induction of alpha/beta interferon (IFN) synthesis and activation of the enzyme PKR, which exerts its...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC153953/ https://ncbi.nlm.nih.gov/pubmed/12692253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.9.5507-5511.2003 |
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