Activation of PKR by Bunyamwera Virus Is Independent of the Viral Interferon Antagonist NSs

Double-stranded RNA (dsRNA) is a by-product of viral RNA polymerase activity, and its recognition is one mechanism by which the innate immune system is activated. Cellular responses to dsRNA include induction of alpha/beta interferon (IFN) synthesis and activation of the enzyme PKR, which exerts its...

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發表在:	J Virol
Principais autores:	Streitenfeld, Hein, Boyd, Amanda, Fazakerley, John K., Bridgen, Anne, Elliott, Richard M., Weber, Friedemann
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 2003
主題:	Pathogenesis and Immunity
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153953/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12692253/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.9.5507-5511.2003
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