Eosin B as a Novel Antimalarial Agent for Drug-Resistant Plasmodium falciparum

4′,5′-Dibromo-2′,7′-dinitrofluorescein, a red dye commonly referred to as eosin B, inhibits Toxoplasma gondii in both enzymatic and cell culture studies with a 50% inhibitory concentration (IC(50)) of 180 μM. As a non-active-site inhibitor of the bifunctional T. gondii dihydrofolate reductase-thymid...

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Autors principals: Massimine, Kristen M., McIntosh, Michael T., Doan, Lanxuan T., Atreya, Chloé E., Gromer, Stephan, Sirawaraporn, Worachart, Elliott, David A., Joiner, Keith A., Schirmer, R. Heiner, Anderson, Karen S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Mechanisms of Action: Physiological Effects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563504/
https://ncbi.nlm.nih.gov/pubmed/16940112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00621-06
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