Eosin B as a Novel Antimalarial Agent for Drug-Resistant Plasmodium falciparum

4′,5′-Dibromo-2′,7′-dinitrofluorescein, a red dye commonly referred to as eosin B, inhibits Toxoplasma gondii in both enzymatic and cell culture studies with a 50% inhibitory concentration (IC(50)) of 180 μM. As a non-active-site inhibitor of the bifunctional T. gondii dihydrofolate reductase-thymid...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Massimine, Kristen M., McIntosh, Michael T., Doan, Lanxuan T., Atreya, Chloé E., Gromer, Stephan, Sirawaraporn, Worachart, Elliott, David A., Joiner, Keith A., Schirmer, R. Heiner, Anderson, Karen S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Mechanisms of Action: Physiological Effects
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563504/
https://ncbi.nlm.nih.gov/pubmed/16940112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00621-06
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge