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Insights into the role of the junctional region of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase
BACKGROUND: Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfDHFR-TS) is a well-defined target of anti-malarial drug, such as pyrimethamine and cycloguanil. Emergence of malaria parasites resistant to these drugs has been shown to be associated with point mutations of the gene c...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3623654/ https://ncbi.nlm.nih.gov/pubmed/23497065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-91 |
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