Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse

The DNA damage-dependent poly(ADP-ribose) polymerases, PARP-1 and PARP-2, homo- and heterodimerize and are both involved in the base excision repair (BER) pathway. Here, we report that mice carrying a targeted disruption of the PARP-2 gene are sensitive to ionizing radiation. Following alkylating ag...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ménissier de Murcia, Josiane, Ricoul, Michelle, Tartier, Laurence, Niedergang, Claude, Huber, Aline, Dantzer, Françoise, Schreiber, Valérie, Amé, Jean-Christophe, Dierich, Andrée, LeMeur, Marianne, Sabatier, Laure, Chambon, Pierre, de Murcia, Gilbert
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156078/
https://ncbi.nlm.nih.gov/pubmed/12727891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg206
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados