XRCC1 Is Specifically Associated with Poly(ADP-Ribose) Polymerase and Negatively Regulates Its Activity following DNA Damage

Poly(ADP-ribose) polymerase (PARP; EC 2.4.2.30) is a zinc-finger DNA-binding protein that detects and signals DNA strand breaks generated directly or indirectly by genotoxic agents. In response to these breaks, the immediate poly(ADP-ribosyl)ation of nuclear proteins involved in chromatin architectu...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Masson, Murielle, Niedergang, Claude, Schreiber, Valérie, Muller, Sylviane, Menissier-de Murcia, Josiane, de Murcia, Gilbert
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1998
Ämnen:
DNA Dynamics and Chromosome Structure
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC108937/
https://ncbi.nlm.nih.gov/pubmed/9584196
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk