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Unified two-metal mechanism of RNA synthesis and degradation by RNA polymerase
In DNA-dependent RNA polymerases, reactions of RNA synthesis and degradation are performed by the same active center (in contrast to DNA polymerases in which they are separate). We propose a unified catalytic mechanism for multisubunit RNA polymerases based on the analysis of its 3′–5′ exonuclease r...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2003
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC156065/ https://ncbi.nlm.nih.gov/pubmed/12727889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg193 |
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