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The (52–96) C-terminal domain of Vpr stimulates HIV-1 IN-mediated homologous strand transfer of mini-viral DNA

Viral integrase (IN) and Vpr are both components of the human immunodeficiency virus type 1 (HIV-1) pre-integration complex. To investigate whether these proteins interact within this complex, we investigated the effects of Vpr and its subdomains on IN activity in vitro. When a 21mer oligonucleotide...

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Detalhes bibliográficos
Main Authors: Bischerour, Julien, Tauc, Patrick, Leh, Hervé, de Rocquigny, Hugues, Roques, Bernard, Mouscadet, Jean-François
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156046/
https://ncbi.nlm.nih.gov/pubmed/12736319
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