HIV-1 Vpr Oligomerization but Not That of Gag Directs the Interaction between Vpr and Gag

During HIV-1 assembly, the viral protein R (Vpr) is incorporated into newly made viral particles via an interaction with the C-terminal domain of the Gag polyprotein precursor Pr55(Gag). Vpr has been implicated in the nuclear import of newly made viral DNA and subsequently in its transcription. In a...

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Bibliographic Details
Main Authors: Fritz, Joëlle V., Dujardin, Denis, Godet, Julien, Didier, Pascal, De Mey, Jan, Darlix, Jean-Luc, Mély, Yves, de Rocquigny, Hugues
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812354/
https://ncbi.nlm.nih.gov/pubmed/19923179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01691-09
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