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The effect of mutations in the HIV-1 nucleocapsid protein on strand transfer in cell-free reverse transcription reactions

Interactions between the nucleocapsid protein (NC) and reverse transcriptase of HIV-1 have been shown to promote the initiation of reverse transcription. We assayed the effect of NC on later events, using a strand transfer system with donor and acceptor HIV RNA templates and found that the presence...

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Main Authors: Hsu, Mayla, Rong, Liwei, Rocquigny, Hugues de, Roques, Bernard P., Wainberg, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC102828/
https://ncbi.nlm.nih.gov/pubmed/10734191
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