Role of common human TRIM5α variants in HIV-1 disease progression

BACKGROUND: The retroviral restriction factor tripartite motif protein (TRIM)5α, is characterized by marked amino acid diversity among primates, including specific clusters of residues under positive selection. The identification of multiple non-synonymous changes in humans suggests that TRIM5α vari...

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Bibliografski detalji
Glavni autori: Goldschmidt, Valérie, Bleiber, Gabriela, May, Margaret, Martinez, Raquel, Ortiz, Millàn, Telenti, Amalio
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2006
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560158/
https://ncbi.nlm.nih.gov/pubmed/16925802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-3-54
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