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Role of common human TRIM5α variants in HIV-1 disease progression

BACKGROUND: The retroviral restriction factor tripartite motif protein (TRIM)5α, is characterized by marked amino acid diversity among primates, including specific clusters of residues under positive selection. The identification of multiple non-synonymous changes in humans suggests that TRIM5α vari...

詳細記述

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書誌詳細
主要な著者: Goldschmidt, Valérie, Bleiber, Gabriela, May, Margaret, Martinez, Raquel, Ortiz, Millàn, Telenti, Amalio
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1560158/
https://ncbi.nlm.nih.gov/pubmed/16925802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-3-54
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