APOBEC3G Genetic Variants and Their Influence on the Progression to AIDS

The cytosine deaminase APOBEC3G, in the absence of the human immunodeficiency virus type 1 (HIV-1) accessory gene HIV-1 viral infectivity factor (vif), inhibits viral replication by introducing G→A hypermutation in the newly synthesized HIV-1 DNA negative strand. We tested the hypothesis that geneti...

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Autori principali: An, Ping, Bleiber, Gabriela, Duggal, Priya, Nelson, George, May, Margaret, Mangeat, Bastien, Alobwede, Irene, Trono, Didier, Vlahov, David, Donfield, Sharyne, Goedert, James J., Phair, John, Buchbinder, Susan, O'Brien, Stephen J., Telenti, Amalio, Winkler, Cheryl A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC521814/
https://ncbi.nlm.nih.gov/pubmed/15452227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.20.11070-11076.2004
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