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Use of a Combined Ex Vivo/In Vivo Population Approach for Screening of Human Genes Involved in the Human Immunodeficiency Virus Type 1 Life Cycle for Variants Influencing Disease Progression

Humans differ substantially with respect to susceptibility to human immunodeficiency virus type 1 (HIV-1). We evaluated variants of nine host genes participating in the viral life cycle for their role in modulating HIV-1 infection. Alleles were assessed ex vivo for their impact on viral replication...

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Detalhes bibliográficos
Main Authors: Bleiber, Gabriela, May, Margaret, Martinez, Raquel, Meylan, Pascal, Ott, Jürg, Beckmann, Jacques S., Telenti, Amalio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235818/
https://ncbi.nlm.nih.gov/pubmed/16188970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.20.12674-12680.2005
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