Individual Contributions of Mutant Protease and Reverse Transcriptase to Viral Infectivity, Replication, and Protein Maturation of Antiretroviral Drug-Resistant Human Immunodeficiency Virus Type 1

Human immunodeficiency virus type 1 (HIV-1) variants resistant to protease (PR) and reverse transcriptase (RT) inhibitors may display impaired infectivity and replication capacity. The individual contributions of mutated HIV-1 PR and RT to infectivity, replication, RT activity, and protein maturatio...

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Detalhes bibliográficos
Main Authors: Bleiber, Gabriela, Munoz, Miguel, Ciuffi, Angela, Meylan, Pascal, Telenti, Amalio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114122/
https://ncbi.nlm.nih.gov/pubmed/11238855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.7.3291-3300.2001
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