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Antiretroviral Activity of Ancestral TRIM5α

The antiretroviral protein TRIM5α is known to have evolved different restriction capacities against various retroviruses, driven by positive Darwinian selection. However, how these different specificities have evolved in the primate lineages is not fully understood. Here we used ancestral protein re...

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Detalhes bibliográficos
Main Authors: Goldschmidt, Valérie, Ciuffi, Angela, Ortiz, Millan, Brawand, David, Muñoz, Miguel, Kaessmann, Henrik, Telenti, Amalio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258955/
https://ncbi.nlm.nih.gov/pubmed/18077724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01828-07
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