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Unique Spectrum of Activity of Prosimian TRIM5α against Exogenous and Endogenous Retroviruses

Lentiviruses, the genus of retrovirus that includes HIV-1, rarely endogenize. Some lemurs uniquely possess an endogenous lentivirus called PSIV (“prosimian immunodeficiency virus”). Thus, lemurs provide the opportunity to study the activity of host defense factors, such as TRIM5α, in the setting of...

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Detalhes bibliográficos
Main Authors: Rahm, Nadia, Yap, Melvyn, Snoeck, Joke, Zoete, Vincent, Muñoz, Miguel, Radespiel, Ute, Zimmermann, Elke, Michielin, Olivier, Stoye, Jonathan P., Ciuffi, Angela, Telenti, Amalio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126249/
https://ncbi.nlm.nih.gov/pubmed/21345948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00075-11
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