Unique Spectrum of Activity of Prosimian TRIM5α against Exogenous and Endogenous Retroviruses

Lentiviruses, the genus of retrovirus that includes HIV-1, rarely endogenize. Some lemurs uniquely possess an endogenous lentivirus called PSIV (“prosimian immunodeficiency virus”). Thus, lemurs provide the opportunity to study the activity of host defense factors, such as TRIM5α, in the setting of...

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Main Authors: Rahm, Nadia, Yap, Melvyn, Snoeck, Joke, Zoete, Vincent, Muñoz, Miguel, Radespiel, Ute, Zimmermann, Elke, Michielin, Olivier, Stoye, Jonathan P., Ciuffi, Angela, Telenti, Amalio
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2011
Assuntos:
Genetic Diversity and Evolution
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126249/
https://ncbi.nlm.nih.gov/pubmed/21345948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00075-11
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