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All Three Variable Regions of the TRIM5α B30.2 Domain Can Contribute to the Specificity of Retrovirus Restriction

Recent studies have revealed the contribution of TRIM5α to retrovirus restriction in cells from a variety of primate species. TRIM5α consists of a tripartite motif (the RBCC domain) followed by a B30.2 domain. The B30.2 domain is thought to be involved in determination of restriction specificity and...

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Detalhes bibliográficos
Main Authors: Ohkura, Sadayuki, Yap, Melvyn W., Sheldon, Tom, Stoye, Jonathan P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563890/
https://ncbi.nlm.nih.gov/pubmed/16912305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00688-06
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