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The Specificity of TRIM5α-Mediated Restriction Is Influenced by Its Coiled-Coil Domain

Retroviruses are both powerful evolutionary forces and dangerous threats to genome integrity. As such, they have imposed strong selective pressure on their hosts, notably triggering the emergence of restriction factors, such as TRIM5α, that act as potent barriers to their cross-species transmission....

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Autors principals: Maillard, Pierre V., Ecco, Gabriela, Ortiz, Millán, Trono, Didier
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876608/
https://ncbi.nlm.nih.gov/pubmed/20219908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02413-09
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