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REMOTE-SITE CONTROL OF AN ACTIVE-SITE FIDELITY CHECKPOINT IN A VIRAL RNA-DEPENDENT RNA POLYMERASE
The kinetic, thermodynamic and structural basis for fidelity of nucleic acid polymerases remains controversial. An understanding of viral RNA-dependent RNA polymerase (RdRp) fidelity has become a topic of considerable interest as a result of recent experiments that show that a two-fold increase in f...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1557591/ https://ncbi.nlm.nih.gov/pubmed/15878882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M503444200 |
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