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Quasispecies diversity determines pathogenesis through cooperative interactions within a viral population
An RNA virus population does not consist of a single genotype; rather, it is an ensemble of related sequences, named quasispecies 1–4. Quasispecies arise from rapid genomic evolution powered by the high mutation rate of RNA viral replication 5–8. While a high mutation rate is dangerous for a virus a...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1569948/ https://ncbi.nlm.nih.gov/pubmed/16327776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04388 |
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