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Molecular Simulation of the Binding of Nerve Growth Factor Peptide Mimics to the Receptor Tyrosine Kinase A

Nerve growth factor (NGF) mimics play an important role for therapies that target the receptor tyrosine kinase A (trkA). The N-terminal fragment of the NGF (N-term@NGF) was previously demonstrated to be an important determinant for affinity and specificity in the binding to trkA. Here we use a varie...

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Bibliografske podrobnosti
Main Authors: Berrera, Marco, Cattaneo, Antonino, Carloni, Paolo
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557562/
https://ncbi.nlm.nih.gov/pubmed/16798810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.083519
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