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cAMP Modulation of the Cytoplasmic Domain in the HCN2 Channel Investigated by Molecular Simulations
The hyperpolarization-activated cyclic nucleotide-modulated (HCN) cation channels are opened by membrane hyperpolarization, while their activation is modulated by the binding of cyclic adenosine monophosphate (cAMP) in the cytoplasm. Here we investigate the molecular basis of cAMP channel modulation...
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Autori principali: | , , |
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Natura: | Artigo |
Lingua: | Inglês |
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Biophysical Society
2006
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Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440727/ https://ncbi.nlm.nih.gov/pubmed/16500960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.071621 |
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