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cAMP Modulation of the Cytoplasmic Domain in the HCN2 Channel Investigated by Molecular Simulations
The hyperpolarization-activated cyclic nucleotide-modulated (HCN) cation channels are opened by membrane hyperpolarization, while their activation is modulated by the binding of cyclic adenosine monophosphate (cAMP) in the cytoplasm. Here we investigate the molecular basis of cAMP channel modulation...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440727/ https://ncbi.nlm.nih.gov/pubmed/16500960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.071621 |
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