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Conformational Dynamics of RNA-Peptide Binding: A Molecular Dynamics Simulation Study

Molecular dynamics simulations of the binding of the heterochiral tripeptide KkN to the transactivation responsive (TAR) RNA of HIV-1 is presented, using an all-atom force field with explicit water. To obtain starting structures for the TAR-KkN complex, semirigid docking calculations were performed...

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Detalhes bibliográficos
Main Authors: Mu, Yuguang, Stock, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367046/
https://ncbi.nlm.nih.gov/pubmed/16239331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.069559
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