CD40 Contributes to Lethality in Acute Sepsis: In Vivo Role for CD40 in Innate Immunity

Sepsis induces an early inflammatory cascade initiated by the innate immune response. This often results in the development of multisystem organ failure. We examined the role of CD40, a costimulatory molecule that is integral in adaptive immunity, by using a murine model of polymicrobial sepsis. CD4...

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में प्रकाशित:	Infect Immun
मुख्य लेखकों:	Gold, Jeffrey A., Parsey, Merdad, Hoshino, Yoshihiko, Hoshino, Satomi, Nolan, Anna, Yee, Herman, Tse, Doris B., Weiden, Michael D.
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	American Society for Microbiology (ASM) 2003
विषय:	Host Response and Inflammation
ऑनलाइन पहुंच:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155725/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12761137/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.6.3521-3528.2003
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