The CD154/CD40 Interaction Required for Retrovirus-Induced Murine Immunodeficiency Syndrome Is Not Mediated by Upregulation of the CD80/CD86 Costimulatory Molecules

C57BL/6 (B6) mice infected with LP-BM5 retroviruses develop disease, including an immunodeficiency similar to AIDS. This disease, murine AIDS (MAIDS), is inhibited by in vivo anti-CD154 monoclonal antibody treatment. The similar levels of insusceptibility of CD40(−/−) and CD154(−/−) B6 mice indicate...

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Detalhes bibliográficos
Main Authors: Green, Kathy A., Cook, W. James, Sharpe, Arlene H., Green, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136728/
https://ncbi.nlm.nih.gov/pubmed/12438641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.24.13106-13110.2002
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