The CD154/CD40 Interaction Required for Retrovirus-Induced Murine Immunodeficiency Syndrome Is Not Mediated by Upregulation of the CD80/CD86 Costimulatory Molecules

C57BL/6 (B6) mice infected with LP-BM5 retroviruses develop disease, including an immunodeficiency similar to AIDS. This disease, murine AIDS (MAIDS), is inhibited by in vivo anti-CD154 monoclonal antibody treatment. The similar levels of insusceptibility of CD40(−/−) and CD154(−/−) B6 mice indicate...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Green, Kathy A., Cook, W. James, Sharpe, Arlene H., Green, William R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136728/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12438641/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.24.13106-13110.2002
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