Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection

Recent data implicates a role for the CD40–CD40 ligand (CD40L) pathway in graft rejection. One potential mechanism is direct costimulation of T cells through CD40L. Alternatively, the ability of CD40 stimulation to induce CD80 (B7-1) and CD86 (B7-2) expression on antigen-presenting cells (APCs) has...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Hancock, Wayne W., Sayegh, Mohamed H., Zheng, Xiang-Guang, Peach, Robert, Linsley, Peter S., Turka, Laurence A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19478/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8943044/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.24.13967
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