CD40 Contributes to Lethality in Acute Sepsis: In Vivo Role for CD40 in Innate Immunity

Sepsis induces an early inflammatory cascade initiated by the innate immune response. This often results in the development of multisystem organ failure. We examined the role of CD40, a costimulatory molecule that is integral in adaptive immunity, by using a murine model of polymicrobial sepsis. CD4...

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Bibliografiset tiedot
Päätekijät: Gold, Jeffrey A., Parsey, Merdad, Hoshino, Yoshihiko, Hoshino, Satomi, Nolan, Anna, Yee, Herman, Tse, Doris B., Weiden, Michael D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2003
Aiheet:
Host Response and Inflammation
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC155725/
https://ncbi.nlm.nih.gov/pubmed/12761137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.6.3521-3528.2003
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