Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice

Centromere protein A (Cenpa for mouse, CENP-A for other species) is a histone H3-like protein that is thought to be involved in the nucleosomal packaging of centromeric DNA. Using gene targeting, we have disrupted the mouse Cenpa gene and demonstrated that the gene is essential. Heterozygous mice ar...

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Cyhoeddwyd yn:	Proc Natl Acad Sci U S A
Prif Awduron:	Howman, Emily V., Fowler, Kerry J., Newson, Ainsley J., Redward, Saara, MacDonald, Andrew C., Kalitsis, Paul, Choo, K. H. Andy
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	National Academy of Sciences 2000
Pynciau:	Biological Sciences
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15551/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10655499/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.3.1148
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