Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice
Centromere protein A (Cenpa for mouse, CENP-A for other species) is a histone H3-like protein that is thought to be involved in the nucleosomal packaging of centromeric DNA. Using gene targeting, we have disrupted the mouse Cenpa gene and demonstrated that the gene is essential. Heterozygous mice ar...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15551/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10655499/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.3.1148 |
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