Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice

Centromere protein A (Cenpa for mouse, CENP-A for other species) is a histone H3-like protein that is thought to be involved in the nucleosomal packaging of centromeric DNA. Using gene targeting, we have disrupted the mouse Cenpa gene and demonstrated that the gene is essential. Heterozygous mice ar...

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Detaylı Bibliyografya
Asıl Yazarlar: Howman, Emily V., Fowler, Kerry J., Newson, Ainsley J., Redward, Saara, MacDonald, Andrew C., Kalitsis, Paul, Choo, K. H. Andy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2000
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC15551/
https://ncbi.nlm.nih.gov/pubmed/10655499
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