Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice

Centromere protein A (Cenpa for mouse, CENP-A for other species) is a histone H3-like protein that is thought to be involved in the nucleosomal packaging of centromeric DNA. Using gene targeting, we have disrupted the mouse Cenpa gene and demonstrated that the gene is essential. Heterozygous mice ar...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Howman, Emily V., Fowler, Kerry J., Newson, Ainsley J., Redward, Saara, MacDonald, Andrew C., Kalitsis, Paul, Choo, K. H. Andy
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 2000
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15551/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10655499/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.3.1148
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