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Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice

Centromere protein A (Cenpa for mouse, CENP-A for other species) is a histone H3-like protein that is thought to be involved in the nucleosomal packaging of centromeric DNA. Using gene targeting, we have disrupted the mouse Cenpa gene and demonstrated that the gene is essential. Heterozygous mice ar...

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主要な著者: Howman, Emily V., Fowler, Kerry J., Newson, Ainsley J., Redward, Saara, MacDonald, Andrew C., Kalitsis, Paul, Choo, K. H. Andy
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2000
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC15551/
https://ncbi.nlm.nih.gov/pubmed/10655499
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